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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
18.18
Human Site:
T492
Identified Species:
30.77
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
T492
T
P
P
L
P
K
G
T
P
P
L
T
P
S
D
Chimpanzee
Pan troglodytes
XP_509445
540
59236
S331
G
T
P
P
L
T
P
S
D
S
P
Q
T
R
T
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
T492
T
P
P
L
P
K
G
T
P
P
L
T
P
S
D
Dog
Lupus familis
XP_534658
709
78944
T492
T
P
P
L
P
K
G
T
P
P
L
T
P
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
T495
T
P
P
L
P
K
G
T
P
P
L
T
P
S
D
Rat
Rattus norvegicus
NP_001099399
476
51796
F267
Q
G
T
P
P
P
L
F
T
P
P
L
P
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
N489
T
P
P
Q
T
P
P
N
F
T
P
P
L
P
R
Chicken
Gallus gallus
Q5F3D1
613
68449
V404
H
P
P
L
P
N
T
V
S
S
L
N
P
S
S
Frog
Xenopus laevis
Q6DD45
743
82926
S477
L
P
R
G
T
P
P
S
T
P
P
N
F
I
P
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
T476
P
K
G
T
P
P
A
T
P
P
T
N
E
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
F344
E
S
Q
S
K
E
N
F
I
K
S
L
G
E
N
Honey Bee
Apis mellifera
XP_001122586
556
62911
K347
D
D
G
Y
K
R
K
K
L
K
T
I
N
S
A
Nematode Worm
Caenorhab. elegans
P34656
453
51815
N244
I
V
W
Y
P
G
F
N
G
E
Q
S
S
L
N
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
T417
P
P
T
P
E
I
A
T
P
P
P
L
P
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
100
100
N.A.
100
20
N.A.
20
46.6
13.3
26.6
N.A.
0
6.6
6.6
33.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
20
N.A.
20
46.6
20
33.3
N.A.
13.3
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
29
% D
% Glu:
8
0
0
0
8
8
0
0
0
8
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
8
15
8
0
0
0
8
0
0
% F
% Gly:
8
8
15
8
0
8
29
0
8
0
0
0
8
0
15
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
8
0
0
8
0
8
0
% I
% Lys:
0
8
0
0
15
29
8
8
0
15
0
0
0
8
0
% K
% Leu:
8
0
0
36
8
0
8
0
8
0
36
22
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
15
0
0
0
22
8
8
15
% N
% Pro:
15
58
50
22
58
29
22
0
43
58
36
8
50
15
15
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
8
0
8
0
0
0
15
8
15
8
8
8
43
8
% S
% Thr:
36
8
15
8
15
8
8
43
15
8
15
29
8
0
8
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _